Does it Matter HOW a Medication Works?

Understanding mechanisms of action can provide reassurance and insight

John Kruse MD, PhD
Wise & Well
Published in
8 min readMar 29, 2024

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Arek Socha / Pixabay

“Hey doc, why are you treating my ADHD with an antidepressant?” Mark asked at a follow-up appointment, having discovered that he was now taking the same medication as his wife — but she was on it for depression. I again explained the ways in which Wellbutrin resembled and differed…

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John Kruse MD, PhD
Wise & Well

Psychiatrist, neuroscientist, father of twins, marathon runner, in Hawaii. 100+ ADHD & mental health videos https://www.youtube.com/@dr.johnkruse6708